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Birch pollen allergy in Europe - Wiley Online Library
...Subsequently, the prev-alence of birch pollen sensitization has also increased. The cross-reactivity and se-quential pollen seasons within the birch homologous group create a prolonged symptomatic allergy period beyond birch pollen alone....
https://onlinelibrary.wiley.com/doi/epdf/10.1111/all.13758

Immunological and Biological Properties of Bet v 4, a Novel Birch ...
...We have isolated a cDNA clone coding for a birch pollen allergen, Bet v 4. The deduced amino acid sequence of Bet v 4 contained two typical EF-hand calcium-binding domains. Sequence similarities of Bet v 4 to calmodulin are primarily confined to the calcium-binding domains. However, significant sequence similarities extending outside the Ca2+-binding sites were found with a recently described ......
https://www.jbc.org/article/S0021-9258(18)38701-5/fulltext

t215 Bet v 1 - Thermo Fisher Scientific
...Explore comprehensive, research-based information about the Bet v 1 allergen. Our guide, backed by clinical data, delivers crucial insights into the allergen's health effects, key characteristics, clinical relevance, prevention strategies, and more....
https://www.thermofisher.com/phadia/us/en/resources/allergen-encyclopedia/t3/t215.html

Ole e 3, a Candidate for in vivo Diagnosis of Polcalcin ... - PubMed
...Ole e 3 enabled diagnosis of polcalcin-sensitized patients, and a good correlation was revealed with ImmunoCAP. A 50% inhibition in IgE binding was obtained with 2.8 ng of Ole e 3 for rBet v 4 and 3.9 ng for rPhl p 7....
https://pubmed.ncbi.nlm.nih.gov/33461195/

Go molecular! - corporate.thermofisher.com
...Management considerations Consider a controlled peanut challenge to rule out peanut allergy, and testing with Bet v 1 (PR-10; t215) to confirm birch sensitisation If Birch pollen sensitised and mono-sensitised to Ara h 8 consider seasonal antihistamines and/or immunotherapy...
https://corporate.thermofisher.com/content/dam/diagnostics/commercial/library-resources/2022%20Allergy%20algorithms_EN.pdf

Allergens and molecular components - Eurofins Scientific
...All RASTs in black in the list are performed with Phadia ThermoFisher SCIENTIFIC's ImmunoCap technique and are covered by COFRAC accreditation and all the tests in blue are performed with the HYCOR technique and are also covered by the COFRAC accreditation....
https://cdnmedia.eurofins.com/european-west/media/38984277/allergen-list.pdf

Birke Allergene ? Fakten, Symptome und Behandlung | Allergy Insider
...Sie möchten mehr erfahren zu einer Birke Allergie? In unseren Allergen-Infoblättern finden Sie einen umfassenden Überblick über alle Phasen des Umgangs mit einer Allergie, von Symptomen bis hin zu Diagnose und Behandlung....
https://www.thermofisher.com/allergy/de/de/allergen-fact-sheets/birch-tree.html

Immunological and Biological Properties of Bet v 4, a Novel Birch ...
...We have isolated a cDNA clone coding for a birch pollen allergen, Bet v 4. The deduced amino acid sequence of Bet v 4 contained two typical EF-hand ca?...
https://www.sciencedirect.com/science/article/pii/S0021925818387015

??????????????? ??????, rBet v 4 Polcalcin, IgE (t220)
...??????????????? ??????, rBet v 4 Polcalcin, IgE (t220) :: ??????????????? ?????????? ??? ?? ?? ?? ????????? ?? ???????? ??????`? ????? ????????. ???? ????????????? ?????????? ???????? ???????????? ?? ?????????? ????? ????? ......
https://dobrobut.com/ua/laboratory/alergokomponent-berezi-rbet-v-4-polcalcin-ige-t220

Calcium-Binding Proteins and Their Role in Allergic Diseases
...The fact that patients who were sensitized to timothy grass pollen, olive, or mugwort pollen showed IgE reactivity to rBet v 4 or rAln g 4 suggested that they shared IgE epitopes with calcium-binding allergens in natural pollen extracts from various plants [10], [11], and, therefore, were postulated to be cross-reactive allergens....
https://www.sciencedirect.com/science/article/pii/S0889856106000877

Cross-Reactivity between Oak and Birch Pollens in Korean Tree ...
...Birch pollen extract was found to be cross-reactive primarily with Bet v 1-homologous allergen from oak pollens in Korea pollinosis patients. Considering the sparseness of birch tree in Korea, oak, especially sawtooth oak may be the main cause of tree pollinosis in Korea, rather than birch....
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951548/

Allergie EUROLINE_8-seitig.indd - euroimmun.de
...The PR-10 proteins such as Bet v 1 of birch pollen and its homologues such as Mal d 1 in apple are labile to heat and denaturation, which can reduce the allergenicity of the proteins and the risk of systemic reactions....
https://www.euroimmun.de/documents/Indications/Allergology/Multiplex-immunoblots/Euroline/DP_3000_I_UK_D.pdf

Calcium binding to wild type rBet v 4 and to Bet v 4 mutants. A ...
...Download scientific diagram | Calcium binding to wild type rBet v 4 and to Bet v 4 mutants. A, bacterial lysates of wild type rBet v 4 were incubated in the presence of 10 mM CaCl 2 and 2 mM EGTA ......
https://www.researchgate.net/figure/Calcium-binding-to-wild-type-rBet-v-4-and-to-Bet-v-4-mutants-A-bacterial-lysates-of_fig3_27274714

Fagales pollen sensitization in a birch-free area: A respiratory cohort ...
...Request PDF | Fagales pollen sensitization in a birch-free area: A respiratory cohort survey using Fagales pollen extracts and birch recombinant allergens (rBet v 1, rBet v 2, rBet v 4) | Birch ......
https://www.researchgate.net/publication/9072521_Fagales_pollen_sensitization_in_a_birch-free_area_A_respiratory_cohort_survey_using_Fagales_pollen_extracts_and_birch_recombinant_allergens_rBet_v_1_rBet_v_2_rBet_v_4

ImmunoCAP? Tree Allergen Components - Thermo Fisher Scientific
...Quantify specific IgE antibodies with ImmunoCAP? Tree Allergen Components down to the molecular level, essential tools to aid in the diagnosis of allergic conditions. IgE antibodies appear in human serum and plasma as a result of sensitization to a specific allergen. Measurement of circulating IgE antibodies provides an objective assessment of sensitization to an allergen at the molecular ......
https://www.thermofisher.com/order/catalog/product/14522501



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