Dietary Reference Values for magnesium | EFSA
...For children aged 10 to < 18 years, an AI for magnesium is set at 300 mg/day for boys and 250 mg/day for girls. For infants aged 7?11 months, an AI for magnesium of 80 mg/day is derived by extrapolating upwards from the estimated magnesium intake in exclusively breast-fed infants aged 0?6 months and by considering observed average intakes ......
https://www.efsa.europa.eu/en/efsajournal/pub/4186
Proposed maximum levels for the addition of magnesium to foods ...
...2.1 Tolerable Upper Intake Level1 (UL) and Dietary Reference Values The former Scientific Committee on Food (SCF) of the European Commission (SCF, 2001) derived a UL of 250 mg/day for the supplementary intake of readily dissociable magnesium salts and compounds such as magnesium oxide taken up via food supplements or fortified foods for ......
https://www.bfr.bund.de/cm/349/proposed-maximum-levels-for-the-addition-of-magnesium-to-foods-including-food-supplements.pdf
Scientific Opinion on Dietary Reference Values for magnesium - EFSA
...A Tolerable Upper Intake Level (UL) was determined by the SCF (2001) based on studies in which mild diarrhoea occurred after ingestion of magnesium supplements and in which information on magnesium intake from foods and beverages was not available....
https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2015.4186
Perspective: Call for Re-evaluation of the Tolerable Upper Intake Level ...
...In 1997, the US Institute of Medicine (IOM) dietary reference intakes (DRI) Committee established a magnesium (Mg) tolerable upper intake level (UL) for adults of 350 mg/d from supplemental intake alone. Diarrhea was the limiting factor. The safety of oral Mg dietary supplements exceeding the UL is currently in debate. Increasing the UL may result in more Mg supplementation, decreasing the ......
https://www.sciencedirect.com/science/article/pii/S2161831323013352
UPDATE ON UPPER INTAKE LEVELS (UL) FOR VITAMINS AND MINERALS IN FOOD ...
...For example, regarding vitamin A, France sets a maximum limit of 1000 µg RE (for the adult population), Italy sets it at 1200 µg RE, while Spain's limit is 3000 µg RE. Conversely, for magnesium, Spain?s maximum daily limit is 250 mg, whereas France and Italy have less restrictive limits of 360 mg and 450 mg, respectively....
https://www.lexsupplements.com/en/blog/update-on-upper-intake-levels-ul-for-vitamins-and-minerals-in-food-supplements
Title of the Technical report - European Food Safety Authority
...Overview on Tolerable Upper Intake Levels as derived by the Scientific Committee on Food (SCF) and the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) The Tolerable Upper Intake Level (UL) is the maximum level of total chronic daily intake of a nutrient (from all dietary sources) which is not expected to pose a risk of adverse health effects to humans (EFSA NDA Panel, 2024a)....
https://www.efsa.europa.eu/sites/default/files/2024-05/ul-summary-report.pdf
CRN?s Updated Evaluation Raises Safe Intake Level for Magnesium ...
...APRIL 29, 2025 - The Council for Responsible Nutrition (CRN), the leading trade association for the dietary supplement and functional food industry, has completed an updated evaluation of magnesium safety, raising its recommended safe upper level (UL) for magnesium supplements to 500 milligrams per day for healthy adults, based on new human clinical data showing that higher levels are well ......
https://www.crnusa.org/newsroom/crns-updated-evaluation-raises-safe-intake-level-magnesium-supplements
Safety of magnesium orotate dihydrate as a novel food pursuant to ...
...This intake level corresponds to around 5000 mg/day oro-tic acid and 400 mg/day magnesium. The Panel notes that this would exceed the established UL for supplemental magnesium of 250 mg/day, therefore the use of the NF could be nutritionally disadvantageous....
https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2025.9528
Opinion on the Tolerable Upper Intake Level of Magnesium
...Based on a NOAEL of 250 mg Mg per day and an uncertainty factor of 1.0 an UL of 250 mg Mg per day can be established for readily dissociable magnesium salts (e.g., chloride, sulphate, aspartate, lactate) and compounds like MgO in nutritional supplements, water, or added to food and beverages....
https://ec.europa.eu/food/fs/sc/scf/out105_en.pdf
Type of Magnesium Salt and Formulation Solubility Determines ...
...The European Food Safety Authority (EFSA) proposes an Adequate Intake of 350 and 300 mg/day for men and women, respectively. Given deficiencies present in over 50% of the normal population, magnesium is currently a popular nutritional supplement....
https://www.academia.edu/87258107/Type_of_Magnesium_Salt_and_Formulation_Solubility_Determines_Bioavailability_of_Magnesium_Food_Supplements
Magnesium citrate malate as a source of magnesium added for ... - EFSA
...The Panel notes that at the proposed maximum use levels of MgCM, the existing tolerable upper intake level for magnesium in nutritional supplements, water, or added to food and beverages (250 mg/day) is exceeded. 2018 European Food Safety Authority. published by John Wiley and Sons Ltd on behalf EFSA Journal of European Food Safety Authority....
https://efsa.onlinelibrary.wiley.com/doi/pdf/10.2903/j.efsa.2018.5484
TOLERABLE UPPER INTAKE LEVELS FOR VITAMINS AND MINERALS
...These opinions present comprehensive evaluations of possible adverse health effects of individual micronutrients at intakes in excess of dietary requirements and, where possible, establish Tolerable Upper Intake Levels (UL) for different population groups. The approach taken was based on the principles of scientific risk assessment....
https://www.efsa.europa.eu/sites/default/files/assets/ndatolerableuil.pdf