Topical calcineurin inhibitors - British Association of Dermatologists
...This leaflet has been written to help you understand more about topical (applied to the skin) calcineurin inhibitors. It explains what they are, how they work, how they are used to treat skin conditions, and where you can find out more about them....
https://www.bad.org.uk/pils/topical-calcineurin-inhibitors
Topical Calcineurin Inhibitors ? Primary Care Treatment Pathway
...? Topical calcineurin inhibitors (TCIs) are a class of steroid-free anti-inflammatory topical treatments used for the treatment of many inflammatory skin diseases such as eczema...
https://www.pcds.org.uk/files/general/TCI-Pathway-May-2025.pdf
Topical calcineurin inhibitors | Prescribing information | Eczema ... - CKS
...Topical calcineurin inhibitors should only be applied to areas of active atopic eczema, which may include areas of broken skin. Both tacrolimus and pimecrolimus are applied as a thin layer to the affected areas, up to twice daily, and may be used on any part of the body, except on mucous membranes....
https://cks.nice.org.uk/topics/eczema-atopic/prescribing-information/topical-calcineurin-inhibitors/
Cutaneous adverse reactions to calcineurin inhibitors - DermNet
...What are the cutaneous side effects of topical calcineurin inhibitors? The most commonly reported side effect of topical calcineurin inhibitors is local skin irritation (burning, pruritus, and erythema) at the application site....
https://dermnetnz.org/topics/cutaneous-adverse-reactions-to-calcineurin-inhibitors
A-Z Conditions & Treatments - BAD Patient Hub
...A-Z of Conditions & Treatments These patient information leaflets (PILs) are specially written by the BAD to help you understand more about a particular skin condition. They inform you what the condition is, what causes it, what can be done about it and where you can find out more information about it....
https://www.skinhealthinfo.org.uk/a-z-conditions-treatments/
PATIENT INFORMATION LEAFLET TOPICAL CALCINEURIN INHIBITORS - cdn.bad.org.uk
...Your healthcare professional will let you know if TCIs are safe for you. WHAT ARE THE COMMON SIDE EFFECTS OF TOPICAL CALCINEURIN INHIBITORS? Common side effects can include: ? Burning or itching when first used. This is a temporary side effect that usually gets better within a few days of continued use....
https://cdn.bad.org.uk/uploads/2021/11/14093251/Topical-calcineurin-Inhibitors-PIL-May-2025.pdf
Topical calcineurin inhibitors factsheet - WWL
...Topical calcineurin inhibitors are treatments that alter the immune system and have been developed for controlling eczema. There are two types available: Tacrolimus ointment (Protopic®) for moderate to severe eczema and Pimecrolimus cream (Elidel®) for mild to moderate eczema....
https://www.wwl.nhs.uk/media/Services/Dermatology%20(Community)/topical_calcineurin_inhibitors_jul18.pdf
Topical Calcineurin Inhibitors (TCIs) - National Eczema Society
...Learn about topical calcineurin inhibitors as an alternative to steroids for treating eczema flare-ups and controlling inflammation....
https://eczema.org/information-and-advice/treatments-for-eczema/topical-calcineurin-inhibitors/
Topical calcineurin inhibitors
...Calcineurin inhibitors (TCIs) block the release of calcineurin in the skin, preventing the release of cytokines; they have immune-modulating and anti-inflammatory properties. Their topical use is recommended as a second line option in the treatment of atopic eczema (Nice GL 2004/ TA 82 2015)....
https://www.pcds.org.uk/clinical-guidance/topical-calcineurin-inhibitors
Calcineurin Inhibitors - Psoriasis Association
...Two commonly prescribed calcineurin inhibitors are Protopic and Elidel. These are only available on prescription ? ask your doctor for more information. Calcineurin inhibitors block the chemical calcineurin. This chemical ?switches on? inflammation in the skin; causing redness and itching....
https://www.psoriasis-association.org.uk/calcineurin-inhibitors