Acute respiratory distress syndrome: causes, pathophysiology, and ...
...ARDS can be precipitated by a variety of causes. The pathophysiology of ARDS is complex and involves the activation and dysregulation of multiple overlapping and interacting pathways of injury, inflammation, and coagulation, both in the lung and systemically....
https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(22)01485-4/fulltext
Acute Respiratory Distress Syndrome ? ARDS - LITFL
...Acute Respiratory Distress Syndrome (ARDS) is an acute diffuse, inflammatory lung injury, leading to increased pulmonary vascular permeability, increased lung weight, and loss of aerated lung tissue with hypoxemia and bilateral radiographic opacities, associated with increased venous admixture, increased physiological dead space and decreased ......
https://litfl.com/acute-respiratory-distress-syndrome-ards/
Acute Respiratory Distress Syndrome - StatPearls - NCBI Bookshelf
...Acute respiratory distress syndrome (ARDS) is a life-threatening condition characterized by poor oxygenation and non-compliant or "stiff" lungs. The disorder is associated with capillary endothelial injury and diffuse alveolar damage....
https://www.ncbi.nlm.nih.gov/books/NBK436002/
Acute respiratory distress syndrome (ARDS) - BMJ Best Practice
...Acute respiratory distress syndrome (ARDS) typically presents with dyspnoea and hypoxaemia, which progress to acute respiratory failure. Common causes are pneumonia, sepsis, aspiration, and severe trauma. Mortality is between 30% and 50%....
https://bestpractice.bmj.com/topics/en-gb/374
Acute Respiratory Distress Syndrome (ARDS): Pathophysiology, Management ...
...Acute Respiratory Distress Syndrome (ARDS) is defined by its acute onset, persistent hypoxemia, and pulmonary infiltrates from a direct or indirect lung injury....
https://www.ijmps.com/article/acute-respiratory-distress-syndrome-ards-pathophysiology-management-and-future-perspectives-38/
Pathophysiological mechanisms of ARDS: a narrative review from ...
...By integrating classical theories with recent research advancements, we provide a comprehensive analysis of how inflammatory mediators, metabolic reprogramming, oxidative stress, and immune dysregulation synergistically drive ARDS onset and progression....
https://respiratory-research.biomedcentral.com/articles/10.1186/s12931-025-03137-5
Pathophysiology of the Acute Respiratory Distress Syndrome
...In this review, some of the key advances made in our knowledge of the pathophysiology of ARDS, based on histopathology, imaging, protein, and transcriptomic biomarkers, are presented....
https://www.criticalcare.theclinics.com/article/S0749-0704(21)00043-9/fulltext
Pathophysiology of acute respiratory distress syndrome
...The evolution towards shock or multiple organ dysfunction syndrome follows paths analogous to the pathophysiology of sepsis. This leads to the impaired oxygenation, which is the central problem of ARDS, as well as to respiratory acidosis....
https://en.wikipedia.org/wiki/Pathophysiology_of_acute_respiratory_distress_syndrome
Pathophysiological mechanisms of ARDS: a narrative review from ...
...By integrating classical theories with recent research advancements, we provide a comprehensive analysis of how inflammatory mediators, metabolic reprogramming, oxidative stress, and immune dysregulation synergistically drive ARDS onset and progression....
https://pmc.ncbi.nlm.nih.gov/articles/PMC11827456/
Acute respiratory distress syndrome: causes, pathophysiology, and ...
...The pathophysiology of ARDS is complex and our understanding is incomplete due to the inherent limitations of animal models for ARDS and the challenges of mechanistic studies in humans, particularly during acute critical illness....
https://www.thelancet.com/pdfs/journals/lancet/PIIS0140-6736(22)01485-4.pdf