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Ehlers-Danlos Syndrome and the Eyes | The EDS Clinic
...Epicanthic Folds: These skin folds covering the inner corner of the eye are not specific to EDS but may appear in some individuals and often coincide with other connective tissue-related features....
https://www.eds.clinic/articles/ehlers-danlos-syndrome-eyes

Ehlers-Danlos Syndrome - EyeWiki
...Epicanthal folds (18.6%), infraorbital creases (29.3%), hypertelorism (8%), ptosis (32%), strabismus (8%), blue sclerae, early tear break-up time (7%), lenticular changes, corneal thinning....
https://eyewiki.org/Ehlers-Danlos_Syndrome

Ehlers-Danlos syndromes and their manifestations in the visual system
...Epicanthal folds are also seen in other subtypes of Ehlers-Danlos syndrome including classical (EDS types I and II) and dermatosparaxis (EDS type VIIC). The repair of hypertelorism improves patient appearance and it would seem likely self-esteem (2, 5, 65)....
https://pmc.ncbi.nlm.nih.gov/articles/PMC9552959/

Classical Type Ehlers-Danlos Syndrome
...Poor wound healing is often seen in classical EDS. A characteristic facial feature has been described. These are epicanthic folds, excess skin on the eyelids, a prematurely aged appearance, and scars on the forehead and chin. The absence of striae or stretch marks has also been noted in classical EDS patients....
https://franklincardiovascular.com/classical-ehlers-danlos-syndrome/

EHLERS-DANLOS SYNDROME-TYPE II - PMC
...Characteristic facial appearance with wide spread eyes & wide nasal bridge [1, 3] was also observed, however epicanthic folds were not present....
https://pmc.ncbi.nlm.nih.gov/articles/PMC5531879/

Ehlers-Danlos Syndrome (EDS)-Children's Eye Wiki
...Ptosis 32% Infraorbital creases 30% Myopia 25% Epicanthal folds 19% Strabismus 8% convergence insufficiency convergence insufficiency lenticular changes Ectopia lentis Ectopia lentis Blue sclerae conjunctivochalasis Dry eye Thin corneal pachymetry and steep keratometry possibly angoid streaks (debatable) only documented present in first report ......
https://childrenseye.org/wiki/doku.php?id=ehlers_danlos_syndrome

Multisystemic manifestations in a cohort of 75 classical Ehlers-Danlos ...
...Current major criteria are (1) skin hyperextensibility plus atrophic scars and (2) generalized joint hypermobility (gJHM). Minor criteria include additional mucocutaneous signs, epicanthal folds, gJHM complications, and an affected first-degree relative....
https://pubmed.ncbi.nlm.nih.gov/32736638/

Epicanthal folds - Ehlers-Danlos Syndromes - Inspire
...Some people who have Hypermobile EDS (hEDS) do have epicanthal folds, though not in large enough numbers/percentages to merit making them a diagnostic criteria....
https://www.inspire.com/groups/eds-and-hsd/discussion/epicanthal-folds/

The Ehlers-Danlos syndrome, a disorder with many faces
...Patient with Ehlers?Danlos syndrome, dermatosparaxis type. Note the typical facial appearance with epicanthic folds, downslanting palpebral fissures, blue sclera, micrognathia, prominent lips and facial scars especially around the mouth....
http://ansedh.org/wp-content/uploads/2017/01/the-ehlers-danlos-syndrome-a-disorder-with-many-faces.pdf

cEDS - The Ehlers Danlos Society
...Learn more about Classical Ehlers-Danlos syndrome (cEDS) with the helpful body map guide to signs and symptoms for each of the EDS types....
https://www.ehlers-danlos.com/ceds/



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