Impact of Incorporating Whole Blood into Hemorrhagic Shock ...
...Background: Use of whole blood (WB) for trauma resuscitation has seen a resurgence. The purpose of this study was to investigate survival benefit of WB across a diverse population of bleeding trauma patients....
https://pubmed.ncbi.nlm.nih.gov/35290259/
Whole Blood Resuscitation for Injured Patients Requiring ... - East
...Potential benefits of WB include improved hemostatic capacity and decreased overall volume requirements when transfusing WB compared to COMP. However, the effect of a WB-based resuscitation strategy on mortality for injured patients remains unclear....
https://www.east.org/education-resources/practice-management-guidelines/details/whole-blood-resuscitation-for-injured-patients-requiring-transfusion-a-systematic-review-metaanalysi
Platelet Transfusion for Trauma Resuscitation - Current Trauma Reports
...Summary While platelet function is altered following trauma, platelets should be transfused in balanced ratios during initial resuscitation. Severe injury and shock can impair platelet function, which can persist for several days following the initial trauma....
https://link.springer.com/article/10.1007/s40719-022-00236-2
Timing to First Whole Blood Transfusion and Survival Following Severe ...
...To evaluate whether earlier timing of first WB transfusion is associated with improved survival at 24 hours and 30 days for adult trauma patients presenting with severe hemorrhage....
https://europepmc.org/article/MED/38294820
The Role of TEG and ROTEM in Damage Control Resuscitation
...Directed methods to combat coagulopathy and attain hemostasis are needed. The available literature regarding viscoelastic testing, including thrombelastography (TEG) and rotational......
https://www.researchgate.net/publication/350425464_The_Role_of_TEG_and_ROTEM_in_Damage_Control_Resuscitation
THOR-AABB Working Party Recommendations for a Prehospital Blood Product ...
...These recommendations cover all aspects of such a program including storing, transporting, and transfusing blood products in the prehospital phase of hemorrhagic resuscitation. Traumatic hemorrhage is a leading cause of death and disability, especially in younger adults (1)....
https://www.tandfonline.com/doi/full/10.1080/10903127.2021.1995089
Nationwide analysis of whole blood hemostatic resuscitation in civilian ...
...There is a paucity of data on its role in civilians where balanced component therapy (CT) resuscitation is the standard of care. The aim of this study was to assess nationwide outcomes of using WB as an adjunct to CT versus CT alone in resuscitating civilian trauma patients....
https://pubmed.ncbi.nlm.nih.gov/32744830/
Whole lot of blood: does more equal better for survival? | Trauma ...
...They found that a ratio of whole blood to RBC ?1 was associated with improved 4-hour and 24-hour survival and significantly reducing overall transfusion needs. Whole blood transfusion offers a swift and efficient means of providing a high-ratio blood transfusion with a superior hemostatic profile....
https://tsaco.bmj.com/content/9/1/e001482
EM Quick Hits 64 Whole Blood Transfusions, Calcium Before Diltiazem in ...
...Evidence: Observational studies in military settings show improved early survival with warm fresh whole blood compared to component therapy (Gurney et al. 2020, Shackelford et al. 2021)....
https://emergencymedicinecases.com/em-quick-hits-april-2025/
Preferential whole blood transfusion during the early resuscitation ...
...Introduction Whole blood (WB) transfusion represents a promising resuscitation strategy for trauma patients. However, a paucity of data surrounding the optimal incorporation of WB into......
https://www.researchgate.net/publication/380058559_Preferential_whole_blood_transfusion_during_the_early_resuscitation_period_is_associated_with_decreased_mortality_and_transfusion_requirements_in_traumatically_injured_patients