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RSV Immunization Guidance for Infants and Young Children
...To prevent severe RSV disease in infants, either maternal RSV vaccination (Pfizer's Abrysvo) or infant immunization with a long-acting RSV monoclonal antibody (nirsevimab or clesrovimab) is recommended. Most infants will not need both maternal vaccination and infant RSV antibodies....
https://www.cdc.gov/rsv/hcp/vaccine-clinical-guidance/infants-young-children.html

Clinical Guidance for RSV Immunizations and Vaccines
...Nirsevimab and clesrovimab are monoclonal antibodies that prevent severe RSV disease and are recommended for infants. Nirsevimab is also recommended for some young children at increased risk for severe RSV....
https://www.cdc.gov/rsv/hcp/vaccine-clinical-guidance/index.html

Recommendations for the Prevention of RSV Disease in Infants and ...
...Nirsevimab and Clesrovimab Nirsevimab and clesrovimab 3,4 are considered the first-line recommended immunization products for administration to infants to protect against medically attended RSV disease. They are long-acting monoclonal antibody products administered as a single dose for administration during an infant?s first RSV ......
https://publications.aap.org/pediatrics/article/156/5/e2025073923/203221/Recommendations-for-the-Prevention-of-RSV-Disease

RSV Immunization Guidance for Infants and Young Children
...To prevent severe RSV disease in infants, either maternal RSV vaccination or infant immunization with the RSV monoclonal antibody (nirsevimab) is recommended. Most infants will not need both. Administration of nirsevimab is recommended during October through March in most of the U.S....
https://restoredcdc.org/www.cdc.gov/rsv/hcp/vaccine-clinical-guidance/infants-young-children.html

AAP updates RSV immunization guidance
...The AAP policy Recommendations for the Prevention of RSV Disease in Infants and Children adds Merck?s clesrovimab (Enflonsia) as one of two monoclonal antibody products available to protect infants under 8 months born during or entering their first RSV season....
https://publications.aap.org/aapnews/news/32837/AAP-updates-RSV-immunization-guidance

Nirsevimab Monoclonal Antibody Memo (2025-2026)
...Nirsevimab is approved for the prevention of RSV LRT disease in neonates and infants born during or entering their first RSV season, and in children up to 24 months of age who remain vulnerable to severe RSV disease in their second RSV season....
https://www.stanfordchildrens.org/content/dam/sch/content-public/pdf/antimicrobial-stewardship-program/nirsevimab.pdf

FDA Approves New Drug to Prevent RSV in Babies and Toddlers
...Premature infants, and those with chronic lung disease of prematurity or significant congenital heart disease, are at highest risk for severe RSV disease....
https://www.fda.gov/news-events/press-announcements/fda-approves-new-drug-prevent-rsv-babies-and-toddlers

RSV Monoclonal Antibodies: A Paradigm Shift in Infant Protection
...Main Findings: Long-acting RSV monoclonal antibodies have shifted infant RSV prevention from a narrow, high-risk prophylaxis model to a broader passive immunization strategy for infants entering their first RSV season....
https://globalrph.com/2026/07/rsv-monoclonal-antibodies-a-paradigm-shift-in-infant-protection/

RSV Prophylaxis: Palivizumab, Nirsevimab, and More
...While palivizumab has been mainly used in high-risk infants, nirsevimab can be used in all newborns prior to RSV season as well as those with risk factors during their second RSV season....
https://www.contagionlive.com/view/rsv-prophylaxis-palivizumab-nirsevimab-and-more

Administration of Nirsevimab for RSV Prophylaxis in Infants: A ... - MDPI
...Nirsevimab, a novel monoclonal antibody (mAb), offers sustained protection against RSV for a minimum of 5 months in neonates and young children....
https://www.mdpi.com/2076-393X/13/5/470

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