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Functional methods for evaluating the efficacy of retinal optogenetic ...
...In this review, each functional assay is discussed in the context of retinal optogenetic therapy with notable examples that have demonstrated vision restoration....
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2026.1812539/pdf
Frontiers | Functional methods for evaluating the efficacy of retinal ...
...In this review, each functional assay is discussed in the context of retinal optogenetic therapy with notable examples that have demonstrated vision restoration....
https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2026.1812539/full
?Grace Borchert? - ?Google Scholar?
...GA Borchert, H Shamsnajafabadi, ML Hu, SR De Silva, SM Downes, ... Real-world six-month outcomes in patients switched to faricimab following partial response to anti-VEGF therapy for......
https://scholar.google.com/citations?user=Qythim8AAAAJ&hl=en
Age-related macular degeneration: suitability of optogenetic therapy ...
...Herein, we review the anatomical changes in GA, discuss the suitability of optogenetic therapeutic sensors in different target cells in pre-clinical models, and consider the advantages and disadvantages of different routes of administration of therapeutic vectors....
https://www.neuroscience.ox.ac.uk/publications/2012979
www.ndcn.ox.ac.uk
...Behavioural tests such as light avoidance, optomotor response and visual discrimination assess functional restoration in vivo. In this review, each functional assay is discussed in the context of retinal optogenetic therapy with notable examples that have demonstrated vision restoration....
https://www.ndcn.ox.ac.uk/team/kanmin-xue/publication_modal/2419123
?Hoda Shamsnajafabadi? - ?Google Scholar?
...?Postdoctoral research scientist, Nuffield Department of Clinical Neurosciences, Oxford University? - ??Cited by 243?? - ?Retinal gene therapy? - ?Optogenetics? - ?CRISPR activation? -......
https://scholar.google.com/citations?user=pOCn6hEAAAAJ&hl=en
Age-related macular degeneration: suitability of optogenetic therapy ...
...In this review, we discuss the feasibility of optogenetic therapy as a therapeutic strategy for GA secondary to AMD. We begin by discussing the retinal degeneration progression, suitable optogenetic sensors, target cells, models and routes of administration....
https://europepmc.org/article/MED/39010943
Checking your browser - reCAPTCHA - PubMed
...Checking your browser before accessing pubmed.ncbi.nlm.nih.gov ... Click here if you are not automatically redirected after 5 seconds....
https://pubmed.ncbi.nlm.nih.gov/37626902/
Age-related macular degeneration: suitability of optogenetic therapy ...
...Herein, we review the anatomical changes in GA, discuss the suitability of optogenetic therapeutic sensors in different target cells in pre-clinical models, and consider the advantages and......
https://www.researchgate.net/publication/381852826_Age-related_macular_degeneration_suitability_of_optogenetic_therapy_for_geographic_atrophy
Grace BORCHERT | DPhil student | MD MMed(Ophth) BBiomed(Hon) BMedSci ...
...Optogenetic therapy is a promising strategy for vision restoration. Functional assays have an important role in assessing the modulation of neural activity in response to light......
https://www.researchgate.net/profile/Grace-Borchert
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