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Improving prime editing with an endogenous small RNA-binding protein
...Guided by these results, we developed a prime editor protein (PE7) fused to the RNA-binding, N-terminal domain of La. This editor improved prime editing with expressed pegRNAs and......
https://www.nature.com/articles/s41586-024-07259-6

Improving prime editing with an endogenous small RNA-binding protein
...Guided by these results, we developed a prime editor protein (PE7) fused to the RNA-binding, N-terminal domain of La. This editor improved prime editing with expressed pegRNAs and engineered pegRNAs (epegRNAs), as well as with synthetic pegRNAs optimized for La binding....
https://storage.prod.researchhub.com/uploads/papers/2024/04/16/s41586-024-07259-6.pdf

Improving prime editing with an endogenous small RNA-binding protein ...
...Guided by these results, we developed a prime editor protein (PE7) fused to the RNA-binding, N-terminal domain of La. This editor improved prime editing with expressed pegRNAs and engineered pegRNAs (epegRNAs), as well as with synthetic pegRNAs optimized for La binding....
https://www.broadinstitute.org/publications/broad1348741

Addgene: Improving prime editing with an endogenous small RNA-binding ...
...Improving prime editing with an endogenous small RNA-binding protein. Nature. 2024 Apr 3. doi: 10.1038/s41586-024-07259-6. PubMed Article. Template for in vitro transcription of PE7. For HSPC-related experiments. HDR donor plasmid for PE7 knockin at AAVS1 locus....
https://www.addgene.org/browse/article/28244001/

Publications ? Adamson Lab
...A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat Cell Biol 14, 318-328 (2012)....
https://www.badamsonlab.com/publications

Improving prime editing with an endogenous small RNA-binding protein
...Guided by these results, we developed a prime editor protein (PE7) fused to the RNA-binding, N-terminal domain of La. This editor improved prime editing with expressed pegRNAs and engineered pegRNAs (epegRNAs), as well as with synthetic pegRNAs optimized for La binding....
https://www.storkapp.me/pubpaper/38570691

Improving prime editing with an endogenous small | ResearchBunny
...A prime editor (PE7) fused to La's RNA-binding domain significantly improved editing efficiency. This study provides insights into prime editing mechanisms and strategies for stabilizing exogenous small RNAs....
https://www.researchbunny.com/papers/improving-prime-editing-with-an-endogenous-small-rna-binding-protein-qsf2

Adamson Lab: A small factor makes a big impact on genome editing
...In a paper that appeared in print in the journal Nature on April 18th, 2024, Princeton scientists Jun Yan and Britt Adamson, along with several colleagues, describe a more efficient prime editor....
https://molbio.princeton.edu/news/2024/adamson-lab-small-factor-makes-big-impact-genome-editing

Improving prime editing with an endogenous small RNA-binding protein
...This editor improved prime editing with expressed (e)pegRNAs and synthetic pegRNAs optimized for La binding. Our results provide key insights into how prime editing components interact with the cellular environment and suggest general strategies for stabilizing exogenous small RNAs therein....
https://www.omicsdi.org/dataset/geo/GSE255003

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